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Fmoc-N-amido-PEG1-acid

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Category Fmoc-N-amido-PEGn-acid
Catalog NO. BPG-2016
Product Name Fmoc-N-amido-PEG1-acid
CAS 1654740-73-4
Molecular Formula C20H21NO5
Molecular Weight 355.38
Fmoc-N-amido-PEG1-acid
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Product Information

Description Fmoc-N-amido-PEG1-acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Fmoc-6-Amino-4-oxahexanoic acid; Fmoc-N-amido-PEG1-acid; Fmoc-NH-PEG1-C2-acid; Fmoc-NH-PEG1-CH2CH2COOH; 6-(Fmoc-amino)-4-oxahexanoic Acid; Fmoc-AEP; Fmoc-PEG1-propionic acid; Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-; 3-[2-(Fmoc-amino)ethoxy]propanoic acid
IUPAC Name 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoic acid
Canonical SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCC(=O)O
InChI InChI=1S/C20H21NO5/c22-19(23)9-11-25-12-10-21-20(24)26-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,18H,9-13H2,(H,21,24)(H,22,23)
InChIKey LHBCOPWWQKLECJ-UHFFFAOYSA-N
Boiling Point 589.9±40.0 °C at 760 mmHg
Purity >98%
Density 1.261±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO
Related CAS 850312-72-0 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Exact Mass 355.14197277
LogP 3.40730
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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