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DNP-PEG3-NH2

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Category DNP-PEGn-NH2
Catalog NO. BPG-1643
Product Name DNP-PEG3-NH2
CAS 132316-46-2
Molecular Formula C14H22N4O7
Molecular Weight 358.35
DNP-PEG3-NH2
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Product Information

Synonyms Benzenamine, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2,4-dinitro-
IUPAC Name N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2,4-dinitroaniline
Canonical SMILES C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NCCOCCOCCOCCN
InChI InChI=1S/C14H22N4O7/c15-3-5-23-7-9-25-10-8-24-6-4-16-13-2-1-12(17(19)20)11-14(13)18(21)22/h1-2,11,16H,3-10,15H2
InChIKey RSSLKEPQOZRVQA-UHFFFAOYSA-N
Boiling Point 545.0±50.0°C (Predicted)
Purity ≥95%
Density 1.322±0.06 g/cm3 (Predicted)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

DNP-PEG3-NH2, a compound known for its versatile nature and multifaceted functional properties, is applied across various domains, showcasing high perplexity and burstiness in its applications:

Bioconjugation: Acting as a pivotal bridge in bioconjugation processes, DNP-PEG3-NH2 facilitates the connection of biomolecules like peptides, proteins, or antibodies to a PEG spacer. This intricate linkage plays a crucial role in creating stable and soluble bioconjugates within biological systems. Notably, the PEG spacer serves a dual function by not only reducing immunogenic responses but also enhancing biocompatibility, especially in therapeutic scenarios.

Drug Delivery: Positioned as a leader in drug delivery systems, DNP-PEG3-NH2 excels in enhancing the efficiency and efficacy of drug molecules by modifying their delivery mechanisms. Through conjugation with DNP-PEG3-NH2, researchers can enhance solubility and pharmacokinetics, thereby optimizing drug targeting and minimizing adverse effects.

Immunology Research: Within the expansive realm of immunology, DNP-PEG3-NH2 plays a crucial role in creating hapten-carrier conjugates essential for antibody production. Acting as a key hapten, the DNP moiety, in synergy with the PEG spacer, ensures optimal recognition by the immune system.

Surface Modification: In the interdisciplinary field of materials science, DNP-PEG3-NH2 is extensively utilized for surface modification of nanoparticles, hydrogels, and various materials. This functionalization enhances material biocompatibility and stability, particularly in applications involving medical devices and biosensors. The incorporation of a PEG segment helps prevent nonspecific binding and fouling, establishing DNP-PEG3-NH2 as a premier choice for a diverse range of biomedical applications.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

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