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Dendro Azide-PEG-Dendro Azide, PEG 10k, G3-G6 (16-128) Azide
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| Category | Dendro Azide-PEG-Dendro Azide |
| Catalog NO. | BPG-1368 |
| Product Name | Dendro Azide-PEG-Dendro Azide, PEG 10k, G3-G6 (16-128) Azide |
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Fast track to get specific molecular weight products:
| Catalog | Molecular Weight | Availability | |
|---|---|---|---|
| BPG-1368-1 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G3 16 Azide | In stock | Inquiry |
| BPG-1368-2 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G4 32 Azide | In stock | Inquiry |
| BPG-1368-3 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G5 64 Azide | In stock | Inquiry |
| BPG-1368-4 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G6 128 Azide | In stock | Inquiry |
| BPG-1368-5 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G3 16 Azide | In stock | Inquiry |
| BPG-1368-6 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G4 32 Azide | In stock | Inquiry |
| BPG-1368-7 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G5 64 Azide | In stock | Inquiry |
| BPG-1368-8 | Dendro Azide-PEG-Dendro Azide, PEG 10k, G6 128 Azide | In stock | Inquiry |
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| Description | Dendro Azide-PEG-Dendro Azide has two identical activated dendritic terminal groups, which can increase the molecular weight of the modified drug and is popular in drug release applications. Drug PEGylation can alter its dispersity and solubility in aqueous solutions. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. |
| Solubility | Soluble in water, DMSO and DMF. Freshly prepared before use. |
| Storage | -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing. |
| References | 1. Fernandez-Megia, Eduardo, Juan Correa, and Ricardo Riguera."Clickable" PEG- Dendritic Block Copolymers. Biomacromolecules, 2006, 7(11): 3104-3111. 2. Gopin, Anna, et al. Enzymatic activation of second-generation dendritic prodrugs: conjugation of self-immolative dendrimers with poly (ethylene glycol) via click chemistry. Bioconjugate chemistry, 2006, 17(6): 1432-1440. |
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Industry News
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- Overview of Liposome Preparation Process
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- PEG-DSPE Block Copolymers and Their Derivatives
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- Pharmacokinetics and Bioanalysis of PEGylated Drugs
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- The PROTAC Technology in Drug Development
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