DBCO-PEG5-NHS ester
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2484 |
| Product Name | DBCO-PEG5-NHS ester |
| CAS | 1378531-80-6 |
| Molecular Formula | C₃₆H₄₃N₃O₁₁ |
| Molecular Weight | 693.74 |
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| Description | DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG5-NHS ester can be used in the synthesis of a series of PROTACs. |
| Synonyms | Azadibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester; DBCO-NHCO-PEG5-NHS ester |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)NCCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42 |
| InChI | InChI=1S/C36H43N3O11/c40-32(37-16-13-33(41)38-27-30-7-2-1-5-28(30)9-10-29-6-3-4-8-31(29)38)14-17-45-19-21-47-23-25-49-26-24-48-22-20-46-18-15-36(44)50-39-34(42)11-12-35(39)43/h1-8H,11-27H2,(H,37,40) |
| InChIKey | VGKLBFTYZNBCQG-UHFFFAOYSA-N |
| Purity | >95% |
| Solubility | DMSO, DMF, DCM |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Industry News
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