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cRGD-PEG-NHS, MW 1k

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Category cRGD-PEG-NHS
Catalog NO. BPG-1552
Product Name cRGD-PEG-NHS, MW 1k
cRGD-PEG-NHS, MW 1k
  • Scheme Design
  • Custom Synthesis
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Product Information

Description Arg-Gly-Asp (RGD) polypeptide is a common tumor active targeting polypeptide that can directly act on tumor targets to form an active targeting effect. The applications of RGD peptides includes inhibition of apoptosis, angiogenesis and tumor formation. RGD peptides are used as coating surfaces for biomaterials to enhance drug delivery and imaging for disease diagnosis. PEGylated RGD can be cross-linked with other molecules via reactive terminal groups on PEG for use in various biomedical studies.
Solubility Soluble in water, DMSO and DMF. Freshly prepared before use.
Storage -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
References 1. Li L, Yang J, Wang W W, et al. Pigment epithelium-derived factor gene loaded in cRGD-PEG-PEI suppresses colorectal cancer growth by targeting endothelial cells. International journal of pharmaceutics, 2012, 438(1-2): 1-10.
2. Zhu Y, Zhang J, Meng F, et al. cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo. Journal of Controlled Release, 2016, 233: 29-38.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

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