Catalog NO.: BPG-1567

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Category COOH-PEGn-COOtBu
Product Name COOH-PEG5-COOtBu
CAS 1309460-29-4
Molecular Formula C18H34O9
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Product Information

Description COOH-PEG5-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Acid-PEG5-t-butyl ester; Acid-PEG5-C2-Boc; HOOCCH2CH2O-PEG4-CH2CH2COOtBu; COOH-PEG5-OtBu; Carboxy-PEG5-t-butyl ester; 2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid; 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester; 4,7,10,13,16-Pentaoxanonadecane-1,19-dioic acid, mono(1,1-dimethylethyl) ester
IUPAC Name 3-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Molecular Weight 394.46
Molecular Formula C18H34O9
InChI InChI=1S/C18H34O9/c1-18(2,3)27-17(21)5-7-23-9-11-25-13-15-26-14-12-24-10-8-22-6-4-16(19)20/h4-15H2,1-3H3,(H,19,20)
Boiling Point 495.2±45.0°C (Predicted)
Purity ≥95%
Density 1.109±0.06 g/cm3 (Predicted)
Solubility Soluble in DCM, DMF, DMSO, Water
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C


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