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COOH-PEG5-COOtBu
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| Category | COOH-PEGn-COOtBu |
| Catalog NO. | BPG-1567 |
| Product Name | COOH-PEG5-COOtBu |
| CAS | 1309460-29-4 |
| Molecular Formula | C18H34O9 |
| Molecular Weight | 394.46 |
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| Description | COOH-PEG5-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. |
| Synonyms | Acid-PEG5-t-butyl ester; Acid-PEG5-C2-Boc; HOOCCH2CH2O-PEG4-CH2CH2COOtBu; COOH-PEG5-OtBu; Carboxy-PEG5-t-butyl ester; 2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid; 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester; 4,7,10,13,16-Pentaoxanonadecane-1,19-dioic acid, mono(1,1-dimethylethyl) ester |
| IUPAC Name | 3-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C18H34O9/c1-18(2,3)27-17(21)5-7-23-9-11-25-13-15-26-14-12-24-10-8-22-6-4-16(19)20/h4-15H2,1-3H3,(H,19,20) |
| InChIKey | ILIIUHKWCBCCNI-UHFFFAOYSA-N |
| Boiling Point | 495.2±45.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.109±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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