COOH-PEG4-COOtBu

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Category	COOH-PEGn-COOtBu
Catalog NO.	BPG-0186
Product Name	COOH-PEG4-COOtBu
CAS	1835759-85-7
Molecular Formula	C16H30O8
Molecular Weight	350.41

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Description	COOH-PEG4-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Acid-PEG4-t-butyl ester; Acid-PEG4-C2-Boc; COOH-PEG4-OtBu; HOOCCH2CH2O-PEG3-CH2CH2COOtBu; 2,2-Dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid; 4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester; 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, mono(1,1-dimethylethyl) ester
IUPAC Name	3-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	CC(C)(C)OC(=O)CCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C16H30O8/c1-16(2,3)24-15(19)5-7-21-9-11-23-13-12-22-10-8-20-6-4-14(17)18/h4-13H2,1-3H3,(H,17,18)
InChIKey	LXMHKDZTUDTSCT-UHFFFAOYSA-N
Boiling Point	460.1±40.0°C (Predicted)
Purity	≥95%
Density	1.107±0.06 g/cm3 (Predicted)
Solubility	Soluble in DCM, DMF, DMSO, Water
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C

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