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Cl-PEG11-acid

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Category Cl-PEGn-acid
Catalog NO. BPG-1528
Product Name Cl-PEG11-acid
Molecular Formula C25H49ClO13
Molecular Weight 593.10
Cl-PEG11-acid
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Product Information

Synonyms Cl-PEG11-CH2CH2COOH; 1-chloro-3,6,9,12,15,18,21,24,27,30,33-undecaoxahexatriacontan-36-oic acid
IUPAC Name 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCl
InChI InChI=1S/C25H49ClO13/c26-2-4-30-6-8-32-10-12-34-14-16-36-18-20-38-22-24-39-23-21-37-19-17-35-15-13-33-11-9-31-7-5-29-3-1-25(27)28/h1-24H2,(H,27,28)
InChIKey XFDVPBANNAAPJO-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C

Cl-PEG11-acid, a versatile polyethylene glycol derivative with manifold applications in chemical and biological research, is showcased here through four key applications, each presented with elevated levels of perplexity and burstiness:

Drug Conjugation: Unleashing the potential of Cl-PEG11-acid, researchers delve into enhancing the solubility and stability of drug compounds through the innovative technique of PEGylation. By strategically attaching PEG chains to drugs, scientists fine-tune their pharmacokinetic properties, leading to optimized drug delivery and extended circulation times. This methodology serves as a cornerstone in pushing forward the frontiers of protein and peptide therapeutic development.

Nanoparticle Functionalization: Venturing into the realm of nanoparticle modification, Cl-PEG11-acid assumes a pivotal role in elevating the surface properties of nanoparticles, bolstering their biocompatibility and stability. Through the precise conjugation of Cl-PEG11-acid to nanoparticles, researchers effectively curb protein adsorption and circumvent immune clearance, thereby enhancing the efficacy of nanoparticles in drug delivery and imaging spheres. This strategic functionalization strategy ensures the sustained efficacy and stability of nanoparticles within the intricate milieu of biological systems, propelling advancements in various biomedical applications.

Surface Coating: Spearheading the creation of anti-fouling surfaces, Cl-PEG11-acid emerges as a vital ingredient in the development of advanced biological and medical devices. By coating surfaces with Cl-PEG11-acid, scientists mitigate nonspecific protein binding and cellular adhesion, thereby preserving the functional integrity and durability of these devices. This pivotal application plays a critical role in driving the evolution of cutting-edge biosensors, implants, and diagnostic tools.

Bioconjugation Chemistry: Serving as a linchpin in bioconjugation processes, Cl-PEG11-acid simplifies the attachment of diverse functional groups to biomolecules, enabling the creation of sophisticated therapeutics and diagnostics. This versatile reagent facilitates the conjugation of proteins, peptides, and antibodies to other molecules, enhancing their properties and enabling targeted applications. The intricate art of bioconjugation, harnessing the power of Cl-PEG11-acid, stands as a foundational pillar in pushing the boundaries of medical research and development, paving the way for novel and impactful advancements in the field of biomedicine.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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