Cl-PEG11-acid
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Category | Cl-PEGn-acid |
Catalog NO. | BPG-1528 |
Product Name | Cl-PEG11-acid |
Molecular Formula | C25H49ClO13 |
Molecular Weight | 593.10 |
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Synonyms | Cl-PEG11-CH2CH2COOH; 1-chloro-3,6,9,12,15,18,21,24,27,30,33-undecaoxahexatriacontan-36-oic acid |
IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCl |
InChI | InChI=1S/C25H49ClO13/c26-2-4-30-6-8-32-10-12-34-14-16-36-18-20-38-22-24-39-23-21-37-19-17-35-15-13-33-11-9-31-7-5-29-3-1-25(27)28/h1-24H2,(H,27,28) |
InChIKey | XFDVPBANNAAPJO-UHFFFAOYSA-N |
Purity | ≥95% |
Storage | Store at 2-8°C |
Cl-PEG11-acid, a versatile polyethylene glycol derivative with manifold applications in chemical and biological research, is showcased here through four key applications, each presented with elevated levels of perplexity and burstiness: Drug Conjugation: Unleashing the potential of Cl-PEG11-acid, researchers delve into enhancing the solubility and stability of drug compounds through the innovative technique of PEGylation. By strategically attaching PEG chains to drugs, scientists fine-tune their pharmacokinetic properties, leading to optimized drug delivery and extended circulation times. This methodology serves as a cornerstone in pushing forward the frontiers of protein and peptide therapeutic development. Nanoparticle Functionalization: Venturing into the realm of nanoparticle modification, Cl-PEG11-acid assumes a pivotal role in elevating the surface properties of nanoparticles, bolstering their biocompatibility and stability. Through the precise conjugation of Cl-PEG11-acid to nanoparticles, researchers effectively curb protein adsorption and circumvent immune clearance, thereby enhancing the efficacy of nanoparticles in drug delivery and imaging spheres. This strategic functionalization strategy ensures the sustained efficacy and stability of nanoparticles within the intricate milieu of biological systems, propelling advancements in various biomedical applications. Surface Coating: Spearheading the creation of anti-fouling surfaces, Cl-PEG11-acid emerges as a vital ingredient in the development of advanced biological and medical devices. By coating surfaces with Cl-PEG11-acid, scientists mitigate nonspecific protein binding and cellular adhesion, thereby preserving the functional integrity and durability of these devices. This pivotal application plays a critical role in driving the evolution of cutting-edge biosensors, implants, and diagnostic tools. Bioconjugation Chemistry: Serving as a linchpin in bioconjugation processes, Cl-PEG11-acid simplifies the attachment of diverse functional groups to biomolecules, enabling the creation of sophisticated therapeutics and diagnostics. This versatile reagent facilitates the conjugation of proteins, peptides, and antibodies to other molecules, enhancing their properties and enabling targeted applications. The intricate art of bioconjugation, harnessing the power of Cl-PEG11-acid, stands as a foundational pillar in pushing the boundaries of medical research and development, paving the way for novel and impactful advancements in the field of biomedicine. |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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