CHO-Ph-CONH-PEG10-NHS ester
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| Category | CHO-Ph-CONH-PEGn-NHS ester |
| Catalog NO. | BPG-1495 |
| Product Name | CHO-Ph-CONH-PEG10-NHS ester |
| Molecular Formula | C35H54N2O16 |
| Molecular Weight | 758.82 |
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| Description | CHO-Ph-CONH-PEG10-NHS ester is a non-cleavable 10-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). |
| Synonyms | Ald-Ph-PEG10-NHS ester; Ald-Ph-PEG10-NHS; Ald-Ph-amido-PEG10-C2-NHS ester; DF-PEG10-NHS; 2,5-dioxopyrrolidin-1-yl 1-(4-formylphenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azapentatriacontan-35-oate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C2=CC=C(C=O)C=C2)=O |
| InChI | InChI=1S/C35H54N2O16/c38-29-30-1-3-31(4-2-30)35(42)36-8-10-44-12-14-46-16-18-48-20-22-50-24-26-52-28-27-51-25-23-49-21-19-47-17-15-45-13-11-43-9-7-34(41)53-37-32(39)5-6-33(37)40/h1-4,29H,5-28H2,(H,36,42) |
| InChIKey | OFOYRYGOLMSRSC-UHFFFAOYSA-N |
| Purity | ≥95% |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
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- Introduction of Polyethylene Glycol (PEG)
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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