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CHO-Ph-CONH-PEG10-acid

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Category	CHO-Ph-CONH-PEGn-acid
Catalog NO.	BPG-0905
Product Name	CHO-Ph-CONH-PEG10-acid
Molecular Formula	C31H51NO14
Molecular Weight	661.74

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Description	CHO-Ph-CONH-PEG10-acid is a small PEG reagent with a benzaldehyde moiety and a terminal carboxylic acid group. The benzaldehyde group is reactive with hydrazide and aminooxy moiety. The terminal carboxylic acid can undergo reactions with primary amines in the presence of activators such as EDC or HATU to form a stable amide bond.
Synonyms	Ald-Ph-PEG10-acid; Ald-Ph-amido-PEG10-C2-acid; Ald-Ph-PEG10-COOH; Ald-Ph-NH-PEG10-COOH; 1-(4-Formylphenyl)-1-oxo-5,8,11,14,17,20,23,26,29,32-decaoxa-2-azapentatriacontan-35-oic acid
IUPAC Name	3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1=CC=C(C=O)C=C1)=O
InChI	InChI=1S/C31H51NO14/c33-27-28-1-3-29(4-2-28)31(36)32-6-8-38-10-12-40-14-16-42-18-20-44-22-24-46-26-25-45-23-21-43-19-17-41-15-13-39-11-9-37-7-5-30(34)35/h1-4,27H,5-26H2,(H,32,36)(H,34,35)
InChIKey	ZUEZXDFKTKTKBV-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

CHO-Ph-CONH-PEG10-acid, a specialized chemical compound prevalent in biochemical and pharmaceutical research, boasts a myriad of applications. Here are four key applications of CHO-Ph-CONH-PEG10-acid, highlighted with elevated perplexity and burstiness:

Drug Delivery Systems: Spearheading drug delivery advancements, CHO-Ph-CONH-PEG10-acid assumes a crucial role in the intricate realm of creating sophisticated drug delivery systems. By linking therapeutic molecules with this compound, researchers can augment drug solubility, stability, and bioavailability. This strategic fusion not only amplifies treatment effectiveness but also mitigates treatment toxicity.

Protein Conjugation: In the sphere of protein modification, CHO-Ph-CONH-PEG10-acid emerges as a central figure in protein conjugation methodologies, facilitating the attachment of proteins with polyethylene glycol (PEG). This process, renowned as PEGylation, enhances the pharmacokinetics and immunogenicity of therapeutic proteins, particularly valuable in formulating enduring biopharmaceuticals that redefine treatment paradigms with unparalleled efficacy.

Surface Modification: Beyond conventional applications, CHO-Ph-CONH-PEG10-acid extends its utility to biomaterial and nanomaterial surface modification. By integrating PEG chains onto material surfaces, this compound elevates biocompatibility and reduces nonspecific protein adsorption, crucial for propelling medical device and biosensor technologies to the forefront of material science innovation.

Bioconjugation Studies: In the domain of bioconjugation research, CHO-Ph-CONH-PEG10-acid stands as a cornerstone in the creation of precisely targeted conjugates with antibodies, peptides, or other ligands. These tailored conjugates find diverse applications in targeted drug delivery, imaging, or diagnostics, offering unparalleled precision in the conjugation process. This adaptability enables the development of customized bioconjugates that push the boundaries of molecular therapeutics and diagnostic technologies.

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