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C12-NBD Phytosphingosine

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Category Extracts
Catalog NO. BPG-3249
Product Name C12-NBD Phytosphingosine
CAS 388566-94-7
Molecular Formula C36H63N5O7
Molecular Weight 677.92
C12-NBD Phytosphingosine
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Product Information

Description C12-NBD Phytosphingosine is a fluorescent derivative of phytosphingosine. Phytosphingosine is a naturally occurring lipid compound localized in skin, kidney and intestines.
Synonyms N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine
Purity >99%
Appearance Powder
Shelf Life 1 Year
Storage Store at -20°C
Hygroscopic No
Light Sensitive No
Percent Composition C 63.78%, H 9.37%, N 10.33%, O 16.52%
References 1. Gupta P, Roy S, Nandi AK. MEDEA-interacting protein LONG-CHAIN BASE KINASE 1 promotes pattern-triggered immunity in Arabidopsis thaliana. Plant Mol Biol. 2020 Feb 25. doi: 10.1007/s11103-020-00982-4. Epub ahead of print. PMID: 32100164. PubMed ID: 32100164.
2. Bae DJ, Seo J, Kim SY, Park SY, Do Yoo J, Pyo JH, Cho W, Cho JY, Kim S, Kim IS. ArhGAP12 plays dual roles in Stabilin-2 mediated efferocytosis: Regulates Rac1 basal activity and spatiotemporally turns off the Rac1 to orchestrate phagosome maturation. Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1595-1607. doi: 10.1016/j.bbamcr.2019.07.003. Epub 2019 Jul 10. PubMed ID: 31301364.
3. Takahashi M, Izawa K, Urai M, Yamanishi Y, Maehara A, Isobe M, Matsukawa T, Kaitani A, Takamori A, Uchida S, Yamada H, Nagamine M, Ando T, Shimizu T, Ogawa H, Okumura K, Kinjo Y, Kitamura T, Kitaura J. The phytosphingosine-CD300b interaction promotes zymosan-induced, nitric oxide-dependent neutrophil recruitment. Sci Signal. 2019 Jan 15;12(564). pii: eaar5514. doi: 10.1126/scisignal.aar5514. PubMed ID: 30647146.

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