Online Inquiry

Bis-PEG5-acetic acid

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category	COOH-CH2-PEGn-CH2-COOH
Catalog NO.	BPG-2011
Product Name	Bis-PEG5-acetic acid
CAS	77855-76-6
Molecular Formula	C14H26O10
Molecular Weight	354.35

Scheme Design
Custom Synthesis
cGMP Manufacturing
Quality Assurance

Product Information
Application
References
Documents
Reviews

Product Information

Description	PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. PEG6-(CH2CO2H)2 is a PEG derivative containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
Synonyms	COOH-CH2-PEG6-CH2-COOH; COOH-CH2-PEG5-CH2-COOH; 3,6,9,12,15,18-Hexaoxaeicosanedioic acid; 3,6,9,12,15,18-Hexaoxaicosane-1,20-dioic acid
IUPAC Name	2-[2-[2-[2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Canonical SMILES	C(COCCOCCOCC(=O)O)OCCOCCOCC(=O)O
InChI	InChI=1S/C14H26O10/c15-13(16)11-23-9-7-21-5-3-19-1-2-20-4-6-22-8-10-24-12-14(17)18/h1-12H2,(H,15,16)(H,17,18)
InChIKey	DCQRSABUSOYSIY-UHFFFAOYSA-N
Boiling Point	524.8±45.0 °C at 760 mmHg
Purity	≥95%
Density	1.234±0.06 g/cm3 (Predicted)
Solubility	Soluble in DMSO, Water
Appearance	Colorless Oily Liquid
Storage	Store at 2-8°C

Reviews

If you have any suggestions or comments about mPEG-Br, please submit a review immediately.

Related Link

Why BOC Sciences？

Large Stock

More than 2000+ products in inventory
Global Delivery

Warehouses in multiple cities to ensure fast delivery
mg to kg

Multi specification for academic research and industrial production
24/7 Technical Support

Strict process parameter control to ensure product quality

Products

Resources

Our Feature

BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.