Biotin-PEG6-NH-Mal
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| Category | Biotin PEG |
| Catalog NO. | BPG-2489 |
| Product Name | Biotin-PEG6-NH-Mal |
| CAS | 1808990-66-0 |
| Molecular Formula | C₃₁H₅₁N₅O₁₁S |
| Molecular Weight | 701.83 |
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| Description | Biotin-PEG6-Mal is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Mal can be used in the synthesis of a series of PROTACs. |
| Synonyms | (+)-Biotin-PEG6-NH-Mal; Biotin-PEG6-Mal; Biotin-PEG6-Maleimide; (+)-Biotin-PEG6-Maleimide |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Canonical SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)NC(=O)N2 |
| InChI | InChI=1S/C31H51N5O11S/c37-26(4-2-1-3-25-30-24(23-48-25)34-31(41)35-30)32-8-11-42-13-15-44-17-19-46-21-22-47-20-18-45-16-14-43-12-9-33-27(38)7-10-36-28(39)5-6-29(36)40/h5-6,24-25,30H,1-4,7-23H2,(H,32,37)(H,33,38)(H2,34,35,41)/t24-,25-,30-/m0/s1 |
| InChIKey | ILVNKONXZBFCPD-QRQMUESOSA-N |
| Purity | >97% |
| Appearance | White Solid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
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