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Biotin-PEG3-Mal
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| Category | Biotin PEG |
| Catalog NO. | BPG-2357 |
| Product Name | Biotin-PEG3-Mal |
| CAS | 1431618-70-0 |
| Molecular Formula | C₂₅H₃₉N₅O₈S |
| Molecular Weight | 569.67 |
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| Description | Biotin-PEG3-Mal is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG3-Mal can be used in the synthesis of a series of PROTACs. |
| Synonyms | (+)-Biotin-PEG3-NH-Mal; (+)-Biotin-PEG3-Maleimide; (+)-Biotin-PEG3-Mal |
| IUPAC Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethyl]pentanamide |
| Canonical SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)NC(=O)N2 |
| InChI | InChI=1S/C25H39N5O8S/c31-20(4-2-1-3-19-24-18(17-39-19)28-25(35)29-24)26-8-11-36-13-15-38-16-14-37-12-9-27-21(32)7-10-30-22(33)5-6-23(30)34/h5-6,18-19,24H,1-4,7-17H2,(H,26,31)(H,27,32)(H2,28,29,35)/t18-,19-,24-/m0/s1 |
| InChIKey | OSIQQRWDJZNBFW-JXQFQVJHSA-N |
| Boiling Point | 905.9±65.0 °C at 760 mmHg |
| Purity | >97% |
| Density | 1.3±0.1 g/cm3 |
| Appearance | White Solid |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Technical Information
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
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