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Azido-PEG8-amine

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Category Azido-PEGn-amine
Catalog NO. BPG-2156
Product Name Azido-PEG8-amine
CAS 857891-82-8
Molecular Formula C18H38N4O8
Molecular Weight 438.52
Azido-PEG8-amine
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Product Information

Description Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms O-(2-Aminoethyl)-O'-(2-azidoethyl)heptaethylene glycol; N3-PEG8-CH2CH2NH2; Azido-PEG8-NH2; N3-PEG8-NH2; 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine
IUPAC Name 2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES C(COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N
InChI InChI=1S/C18H38N4O8/c19-1-3-23-5-7-25-9-11-27-13-15-29-17-18-30-16-14-28-12-10-26-8-6-24-4-2-21-22-20/h1-19H2
InChIKey ZSFGTBJYBWJOLZ-UHFFFAOYSA-N
Purity ≥90%
Appearance Colorless or Light Yellowish Liquid
Storage Store at 2-8°C
Exact Mass 438.26896418
LogP 0.54126
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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