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Azido-PEG6-propionic acid
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| Category | Azido-PEGn-Acid |
| Catalog NO. | BPG-2054 |
| Product Name | Azido-PEG6-propionic acid |
| CAS | 361189-66-4 |
| Molecular Formula | C15H29N3O8 |
| Molecular Weight | 379.41 |
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| Description | Azido-PEG6-propionic acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | Azido-PEG6-acid;N3-PEG6-COOH; Azido-PEG6-C2-acid; Azido-PEG6-Acid; 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid; Azide-PEG6-COOH; 3,6,9,12,15,18-Hexaoxaheneicosan-21-oic acid, 1-azido-; N3-PEG6-CH2CH2COOH |
| IUPAC Name | 3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCN=[N+]=N)C(=O)O |
| InChI | InChI=1S/C15H29N3O8/c16-18-17-2-4-22-6-8-24-10-12-26-14-13-25-11-9-23-7-5-21-3-1-15(19)20/h16H,1-14H2/p+1 |
| InChIKey | WCCGWCQBPNHUPZ-UHFFFAOYSA-O |
| Purity | >95% |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Related CAS | 1167575-20-3 (polymer) |
| Appearance | Transparent Liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 379.19546489 |
| LogP | 0.32376 |
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Resources
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Technical Information
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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