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Azido-PEG5-propionic acid

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-1978
Product Name Azido-PEG5-propionic acid
CAS 1425973-16-5
Molecular Formula C13H25N3O7
Molecular Weight 335.35
Azido-PEG5-propionic acid
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Product Information

Description Azido-PEG5-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms Azido-PEG5-acid;N3-PEG5-COOH; Azido-PEG5-C2-acid; Azido-PEG5-Acid; 1-Azido-3,6,9,12,15-pentaozaoctadecan-18-oic acid; 3-[(14-Azido-3,6,9,12-tetraoxatetradec-1-yl)oxy]propanoic acid
IUPAC Name 3-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)O
InChI InChI=1S/C13H25N3O7/c14-16-15-2-4-20-6-8-22-10-12-23-11-9-21-7-5-19-3-1-13(17)18/h1-12H2,(H,17,18)
InChIKey DPJUPQILWDVIKK-UHFFFAOYSA-N
Purity >98.0%
Solubility Soluble in DMSO (10 mm)
Related CAS 1167575-20-3 (polymer)
Appearance Pale Yellow or Colorless Oily Liquid
Shelf Life 0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage Store at 2-8°C
LogP -1.78

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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