Azido-PEG5-NHS ester
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| Category | Azido-PEGn-NHS ester |
| Catalog NO. | BPG-2146 |
| Product Name | Azido-PEG5-NHS ester |
| CAS | 1433996-86-1 |
| Molecular Formula | C17H28N4O9 |
| Molecular Weight | 432.43 |
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| Description | Azido-PEG5-NHS ester is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG5-NHS ester can be used in the synthesis of a series of PROTACs. |
| Synonyms | Azido-PEG5-CH2CO2-NHS; N3-PEG5-C2-NHS ester; N3-PEG5-CH2CH2COONHS Ester; 1-[(1-Azido-18-oxo-3,6,9,12,15-pentaoxaoctadecan-18-yl)oxy]-2,5-pyrrolidinedione; 2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-] |
| InChI | InChI=1S/C17H28N4O9/c18-20-19-4-6-26-8-10-28-12-14-29-13-11-27-9-7-25-5-3-17(24)30-21-15(22)1-2-16(21)23/h1-14H2 |
| InChIKey | UBITXOFSGXNPBW-UHFFFAOYSA-N |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
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- Enzyme-linked immunosorbent assay (ELISA) Technique
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- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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Industry News
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- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- Hyaluronic Acid & PEGylated Hyaluronic Acid
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- Lipid Classification and Drug Delivery Systems
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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