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Azido-PEG4-propionic acid

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-1898
Product Name Azido-PEG4-propionic acid
CAS 1257063-35-6
Molecular Formula C11H21N3O6
Molecular Weight 291.30
Azido-PEG4-propionic acid
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Product Information

Description Azido-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms Azido-PEG4-acid;N3-PEG4-COOH; Azido-PEG4-C2-acid; Azido-PEG4-Acid; N3-PEG4-CH2CH2COOH; 1-Azido-3,6,9,12-tetraoxapentadecan-15-oic acid; 15-Azido-4,7,10,13-tetraoxapentadecanoic acid
IUPAC Name 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)O
InChI InChI=1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16)
InChIKey BODPHGOBXPGJKO-UHFFFAOYSA-N
Purity ≥95%
Solubility Soluble in DMSO (10 mm)
Related CAS 1167575-20-3 (polymer)
Appearance Colorless to light orange to yellow clear liquid
Storage Store at 2-8°C
Exact Mass 291.14303540
LogP 0.29056
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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