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Azido-PEG4-amine

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Category Azido-PEGn-amine
Catalog NO. BPG-1849
Product Name Azido-PEG4-amine
CAS 951671-92-4
Molecular Formula C10H22N4O4
Molecular Weight 262.31
Azido-PEG4-amine
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Product Information

Description N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Synonyms 14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane
IUPAC Name 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES C(COCCOCCOCCOCCN=[N+]=[N-])N
InChI InChI=1S/C10H22N4O4/c11-1-3-15-5-7-17-9-10-18-8-6-16-4-2-13-14-12/h1-11H2
InChIKey ZMBGKXBIVYXREN-UHFFFAOYSA-N
Purity ≥95%
Density 1.10 g/mL
Solubility Soluble in DCM, DMF, DMSO, Water
Appearance Colorless to Light Yellow to Light Orange Liquid
Storage Store at 2-8°C
Exact Mass 262.16410520
LogP 0.47486
Pictogram(s) Corrosive, Irritant
Signal Danger
Precautionary Statement Codes P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501

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