Azido-PEG1-CH2COOH
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Azido-PEGn-CH2COOH |
Catalog NO. | BPG-0846 |
Product Name | Azido-PEG1-CH2COOH |
CAS | 79598-48-4 |
Molecular Formula | C4H7N3O3 |
Molecular Weight | 145.12 |
![Azido-PEG1-CH2COOH](https://resource.bocsci.com/structure/79598-48-4.gif)
- Scheme Design
- Custom Synthesis
- cGMP Manufacturing
- Quality Assurance
- Product Information
- Application
- References
- Documents
- Reviews
Description | Azido-PEG1-CH2CO2H is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. |
Synonyms | Azido-PEG1-CH2CO2H;2-azidoethoxyacetic acid; (2-Azidoethyl)oxyacetic Acid; Acetic acid, (2-azidoethoxy)-; N3-PEG1-CH2CO2H; Azido-PEG1-acetic acid |
IUPAC Name | 2-(2-azidoethoxy)acetic acid |
Canonical SMILES | C(COCC(=O)O)N=[N+]=[N-] |
InChI | InChI=1S/C4H7N3O3/c5-7-6-1-2-10-3-4(8)9/h1-3H2,(H,8,9) |
InChIKey | USTXYASKHZDVMV-UHFFFAOYSA-N |
Purity | ≥95% |
Solubility | Soluble in DCM, Water |
Appearance | Yellowish Oily Matter |
Storage | Store at 2-8°C |
Azido-PEG1-CH2COOH, a widely utilized chemical compound in bioconjugation and pharmaceutical research, offers a multitude of applications characterized by high perplexity and burstiness. Bioconjugation: In the realm of bioconjugation, Azido-PEG1-CH2COOH emerges as a pivotal player owing to its capacity to functionally tether biomolecules together. Leveraging click chemistry, researchers can seamlessly affix peptides, proteins, or nucleic acids to this compound, heralding a crucial step in crafting targeted drug delivery systems and diagnostic tools with precision. Pharmaceutical Development: Within the domain of pharmaceutical research, Azido-PEG1-CH2COOH assumes a crucial role in tailoring drug candidates to enhance their solubility, stability, and bioavailability. The incorporation of its PEG component aids in mitigating immunogenic responses and extending the half-life of therapeutic agents, particularly benefiting biologics and intricate drugs necessitating meticulous delivery and controlled release. Surface Modification: Azido-PEG1-CH2COOH's versatility extends to surface modification applications, where it is instrumental in enhancing the biocompatibility of diverse materials and mitigating non-specific binding occurrences. By affixing this compound to surfaces of medical devices and implants, it serves as a shield against protein adsorption and cellular adhesion, underpinning the development of safer and more efficient biomedical implants. Chemical Biology: In the dynamic realm of chemical biology, researchers harness the potential of Azido-PEG1-CH2COOH to delve into cellular processes and interactions with unparalleled depth. Through the tagging of biomolecules with this compound, scientists gain the ability to monitor and visualize biological phenomena using fluorescence and other detection techniques. This methodological approach not only facilitates the exploration of complex biological systems but also aids in the revelation of novel biomolecular interactions and functionalities. |
Reviews
If you have any suggestions or comments about mPEG-Br, please submit a review immediately.
Why BOC Sciences?
-
Large Stock
More than 2000+ products in inventory
-
Global Delivery
Warehouses in multiple cities to ensure fast delivery
-
mg to kg
Multi specification for academic research and industrial production
-
24/7 Technical Support
Strict process parameter control to ensure product quality
Products
- Lipids
- PEG Derivatives by Structure
-
PEG Derivatives by Functional Group
- Acrylate/Acrylamide/Methacrylate PEG
- Aldehyde (Ald/CHO)PEG
- Alkyne PEG
- Amino PEG, PEG amine(-NH2)
- Azide PEG, Azido PEG(-N3)
- Biotin PEG
- Boc/Fmoc protected amine PEG
- Carboxylic Acid(-COOH) PEG
- Cholesterol PEG
- DBCO PEG
- DNP PEG
- DSPE PEG
- Epoxide glycidyl ether PEG
- FITC PEG
- Folate PEG
- Halide (chloride, bromide) PEG
- Hydrazide PEG
- Hydroxyl(-OH) PEG
- Maleimide(-MAL) PEG
- NHS ester PEG
- Nitrophenyl carbonate (NPC) PEG
- Norbornene PEG
- Olefin/Alkene/Vinyl PEG
- Orthopyridyl disulfide (OPSS) PEG
- Phosphate PEG
- Rhodamine PEG
- SCM PEG
- Silane PEG
- SPDP PEG
- Sulfonate (tosyl, mesyl, tresyl) PEG
- tert-Butyl protected carboxylate PEG
- Thiol(-SH) PEG
- Vinylsulfone PEG
- PEG Copolymers
-
PEG Raw Materials
- Small-molecule Polyethylene Glycol
- Polyethylene Glycol 1000
- Polyethylene Glycol 10000
- Polyethylene Glycol 1500
- Polyethylene Glycol 200
- Polyethylene Glycol 2000
- Polyethylene Glycol 20000
- Polyethylene Glycol 400
- Polyethylene Glycol 4000
- Polyethylene Glycol 600
- Polyethylene Glycol 6000
- Polyethylene Glycol 800
- Polyethylene Glycol 8000
Resources
-
Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
-
Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
![PEGylation of Peptides and Proteins](/peg/images/pcSide-pic2.png)
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
Learn More
APPLICATIONS
![APPLICATIONS](/peg/images/pcSide-pic3.png)
PEG linkers For Drug
Improved Circulation Half-Life
Learn More
Have Customer Reviewed On Us?
Chat With Us