Amino-PEG6-t-butyl ester
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| Category | Amino-PEGn-COOtBu |
| Catalog NO. | BPG-2104 |
| Product Name | Amino-PEG6-t-butyl ester |
| CAS | 1286281-32-0 |
| Molecular Formula | C19H39NO8 |
| Molecular Weight | 409.51 |
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| Description | NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | Amino-PEG6-COOtBu; H2N-PEG6-CH2CH2COOtBu; tert-butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate |
| IUPAC Name | tert-butyl 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCN |
| InChI | InChI=1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3 |
| InChIKey | QGSFECNPSLZGGT-UHFFFAOYSA-N |
| Purity | 98.0 % |
| Solubility | 10 mm in DMSO |
| Appearance | White or off-white solid |
| Storage | Store at -5 ℃, keep in dry and avoid sunlight. |
| Exact Mass | 409.2675672 |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
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- What is Click Chemistry?
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- What is Methoxy Polyethylene Glycol (mPEG)?
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