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Amino-PEG6-propionic acid

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-2009
Product Name Amino-PEG6-propionic acid
CAS 905954-28-1
Molecular Formula C15H31NO8
Molecular Weight 353.41
Amino-PEG6-propionic acid
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Product Information

Description NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms 1-Amino-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid; Amino-PEG6-acid
IUPAC Name 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCOCCOCCN)C(=O)O
InChI InChI=1S/C15H31NO8/c16-2-4-20-6-8-22-10-12-24-14-13-23-11-9-21-7-5-19-3-1-15(17)18/h1-14,16H2,(H,17,18)
InChIKey PVRGRRPCHFTMMD-UHFFFAOYSA-N
Boiling Point 481.0±45.0 °C at 760 mmHg
Purity >98.0%
Density 1.1±0.1 g/cm3
Solubility 10 mm in DMSO
Related CAS 1818294-41-5 (polymer) 196936-04-6 (polymer)
Appearance Solid
Shelf Life ≥ 2 years
Storage Store at -20 °C, keep in dry and avoid sunlight.
LogP 0.21970
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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