Acid-PEG8-NHS ester
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| Category | Acid-PEGn-NHS ester |
| Catalog NO. | BPG-1030 |
| Product Name | Acid-PEG8-NHS ester |
| Molecular Formula | C24H41NO14 |
| Molecular Weight | 567.59 |
- Scheme Design
- Custom Synthesis
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| Description | Acid-PEG8-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. |
| Synonyms | Acid-C2-PEG8-NHS ester; COOH-PEG8-SPA; COOH-PEG8-NHS; 28-((2,5-dioxopyrrolidin-1-yl)oxy)-28-oxo-4,7,10,13,16,19,22,25-octaoxaoctacosanoic acid |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O |
| InChI | InChI=1S/C24H41NO14/c26-21-1-2-22(27)25(21)39-24(30)4-6-32-8-10-34-12-14-36-16-18-38-20-19-37-17-15-35-13-11-33-9-7-31-5-3-23(28)29/h1-20H2,(H,28,29) |
| InChIKey | SFCNXTZPMPHAFG-UHFFFAOYSA-N |
| Purity | ≥95% |
| Appearance | Pale Yellow Oily Matter |
| Storage | Store at 2-8°C |
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Resources
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Technical Information
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- Introduction of Polyethylene Glycol (PEG)
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Industry News
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- Lipid Classification and Drug Delivery Systems
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- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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PEGylation of Peptides
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