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3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol

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Category	Propargyl-PEGn-alcohol
Catalog NO.	BPG-1871
Product Name	3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol
CAS	1036204-60-0
Molecular Formula	C13H24O6
Molecular Weight	276.33

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Description	3,6,9,12,15-Pentaoxaoctadec-17-yn-1-ol is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.
Synonyms	Propargyl-PEG5-OH; Propargyl-PEG6-alcohol; Propyne-PEG5-OH; Alkyne-PEG5-OH; 2-[2-[2-[2-[2-(Propargyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
IUPAC Name	2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES	C#CCOCCOCCOCCOCCOCCO
InChI	InChI=1S/C13H24O6/c1-2-4-15-6-8-17-10-12-19-13-11-18-9-7-16-5-3-14/h1,14H,3-13H2
InChIKey	IDULHQAZDNBPID-UHFFFAOYSA-N
Boiling Point	368.1±37.0 °C at 760 mmHg
Purity	>95%
Density	1.078±0.06 g/cm3 (Predicted)
Solubility	Soluble in DCM, DMF, DMSO
Related CAS	32199-97-6 (polymer)
Appearance	Pale Yellow Oily Liquid
Application	Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Alkyne-PEG5-OH (Propargyl-PEG5-alcohol) is a PEG derivative containing a hydroxyl group and a propargyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
Storage	Store at 2-8°C

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