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2,5-Dioxopyrrolidin-1yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate

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Category	Small-molecule Maleimide PEG
Catalog NO.	BPG-4359
Product Name	2,5-Dioxopyrrolidin-1yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate
Molecular Formula	C12H12N2O6
Molecular Weight	280.2

2,5-Dioxopyrrolidin-1yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate

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Description	2,5-Dioxopyrrolidin-1yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate is an aliphatic linker featuring both an NHS ester and a maleimide. The NHS group is easily displaced by amine-containing molecules while maleimide is a thiol-specific covalent linker which is used to label reduced cysteines in proteins.
Synonyms	GMBS; 80307-12-6; 4-Maleimidobutyric acid N-succinimidyl ester; N-(gamma-Maleimidobutyryloxy)succinimide; 2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate; GMBS Crosslinker; 4-Maleimidobutyric acid N-hydroxysuccinimide ester; 2,5-Dioxopyrrolidin-1yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)butanoate
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCCN2C(=O)C=CC2=O
InChI	InChI=1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
InChIKey	PVGATNRYUYNBHO-UHFFFAOYSA-N
Storage	-20°C
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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