(γ)PGA-PEG-(γ)PGA, MW 1k

  • Catalog No.
  • BPG-1588
  • Product Name
  • (γ)PGA-PEG-(γ)PGA, MW 1k
  • Alias
  • γ-glutamic acid-PEG-γ-glutamic acid
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • Polyglutamic acid (PGA) is a new class of biodegradable polymers. It is non-toxic to organisms and non-immunogenic. It has no side effects and has good biocompatibility. Highly hydrophobic PGA coupled with water-soluble PEG forms excellent carriers for drug delivery. The various reactive terminal groups on the PEG can crosslink with different molecules. PEG-PGA derivatives are good drug crosslinkers as well as drug delivery vehicles.
  • References
  • 1. Akagi T, Higashi M, Kaneko T, et al. Hydrolytic and enzymatic degradation of nanoparticles based on amphiphilic poly (γ-glutamic acid)-graft-L-phenylalanine copolymers. Biomacromolecules, 2006, 7(1): 297-303.
    2. Akagi T, Kaneko T, Kida T, et al. Multifunctional conjugation of proteins on/into bio-nanoparticles prepared by amphiphilic poly (γ-glutamic acid).Journal of Biomaterials Science, Polymer Edition, 2006, 17(8): 875-892.

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