Synonyms:Dibenzocyclooctyne PEG; Dibenzocyclooctyne polyethylene glycol
Dibenzocyclooctyne (DBCO) reagent can be used to label biomolecules and make them spontaneously azide. DBCO and azide can undergo a click chemical reaction without a copper catalyst, which is fast, mild, biocompatible, and quite reduces reaction toxicity. Polyethylene Glycol (PEG) is definitely beneficial to improve the solubility and stability of biomolecules, reduce the immunogenicity of proteins and peptides, and also inhibit non-specific binding on the surface of charged molecules. DBCO-PEG, as a kind of PEG derivative that can undergo copper-free click chemistry, has rapid movement and great stability in buffer. Those DBCO-PEGs have wide application in medical research, drug release, biotechnology, medical equipment, biopolymer materials and so on.
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