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m-PEG8-COOH

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Category Small-molecule Methoxy Linear PEG (mPEG)
Catalog NO. BPG-2108
Product Name m-PEG8-COOH
CAS 1093647-41-6
Molecular Formula C18H36O10
Molecular Weight 412.47
m-PEG8-COOH
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Product Information

Description m-PEG8-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms mPEG7-propionic acid; m-PEG8-acid; 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid; mPEG7-CH2CH2COOH; 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid; MPEG7-OCH2CH2COOH
IUPAC Name 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES COCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI InChI=1S/C18H36O10/c1-21-4-5-23-8-9-25-12-13-27-16-17-28-15-14-26-11-10-24-7-6-22-3-2-18(19)20/h2-17H2,1H3,(H,19,20)
InChIKey JHUSQXBQANBSDC-UHFFFAOYSA-N
Boiling Point 503.0±50.0 °C at 760 mmHg
Flash Point 164.2±23.6 °C
Purity ≥95%
Density 1.111±0.06 g/cm3 (Predicted)
Solubility Soluble in DCM, DMF, DMSO, Water
Appearance Pale Yellow Oily Liquid
Storage Store at 2-8°C
Exact Mass 412.23084734

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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