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mPEG6-NHS ester

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Category Small-molecule Methoxy Linear PEG (mPEG)
Catalog NO. BPG-2124
Product Name mPEG6-NHS ester
CAS 1449390-12-8
Molecular Formula C18H31NO10
Molecular Weight 421.44
mPEG6-NHS ester
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Product Information

Description m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms 2,5-dioxopyrrolidin-1-yl 2,5,8,11,14,17-hexaoxaicosan-20-oate
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES COCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChI InChI=1S/C18H31NO10/c1-23-6-7-25-10-11-27-14-15-28-13-12-26-9-8-24-5-4-18(22)29-19-16(20)2-3-17(19)21/h2-15H2,1H3
InChIKey KIIPLYSZOISNAS-UHFFFAOYSA-N
Boiling Point 502.6±60.0 °C at 760 mmHg
Flash Point 257.8±32.9 °C
Purity >98.0%
Density 1.2±0.1 g/cm3
Solubility 10 mm in DMSO
Appearance Colorless Liquid
Shelf Life 0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Storage Store at -20 °C, keep in dry and avoid sunlight.

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PEGylation of Peptides and Proteins

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