mPEG-PLGA, MW 1k

  • Catalog No.
  • BPG-1458
  • Product Name
  • mPEG-PLGA, MW 1k
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • The compound coupled with polyethylene glycol and polylactic acid-glycolic acid copolymer is a degradable functional high molecular organic compound. PLGA-PEG derivatives with good biocompatibility, non-toxic, good capsular and film forming properties are widely used in pharmaceutical, medical engineering materials and modern industrial fields. PLGA-PEG derivatives can be used as drug-loaded microspheres, vesicles, microcapsules and micelles for sustained release and controlled release of drugs.
  • References
  • 1. Avgoustakis K, Beletsi A, Panagi Z, et al. Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles. International journal of pharmaceutics, 2003, 259(1-2): 115-127.
    2. Liu P, Yu H, Sun Y, et al. A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery. Biomaterials, 2012, 33(17): 4403-4412.

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