mPEG-PLA, MW 1k

  • Catalog No.
  • BPG-1414
  • Product Name
  • mPEG-PLA, MW 1k
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • Polyethylene glycol and polylactic acid coupled compounds are widely used in the field of biomedicine. Drugs modified by the PEG-PLA series of derivatives have better water solubility, encapsulation efficiency and drug loading. Polylactic acid (PLA) is a new type of biomaterial that is a renewable biodegradable material. PLA can be used to prepare novel targeting products such as micelles or vesicles. PLA-PEG derivatives can be applied to targeted drug delivery systems.
  • References
  • 1. Dong, Yuancai, and Si-Shen Feng. Methoxy poly (ethylene glycol)-poly (lactide)(MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs. Biomaterials, 2004, 25(14): 2843-2849.
    2. Dong, Yuancai, and Si-Shen Feng. in vitro and in vivo evaluation of methoxy polyethylene glycol-polylactide (MPEG-PLA) nanoparticles for small-molecule drug chemotherapy. Biomaterials, 2007, 28(28): 4154-4160.

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