mPEG-PLA-PAsp, MW 1k

  • Catalog No.
  • BPG-1419
  • Product Name
  • mPEG-PLA-PAsp, MW 1k
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • Polyethylene glycol and polylactic acid coupled compounds are widely used in the field of biomedicine. Drugs modified by the PEG-PLA series of derivatives have better water solubility, encapsulation efficiency and drug loading. Polylactic acid (PLA) is a new type of biomaterial that is a renewable biodegradable material. PLA can be used to prepare novel targeting products such as micelles or vesicles. PLA-PEG derivatives can be applied to targeted drug delivery systems.
  • References
  • 1. Oh J K. Polylactide (PLA)-based amphiphilic block copolymers: synthesis, self-assembly, and biomedical applications. Soft Matter, 2011, 7(11): 5096-5108.
    2. Tan L W, Ma B Y, Chen L J, et al. Toxicity evaluation and anti-tumor study of docetaxel loaded mPEG-polyester micelles for breast cancer therapy.Journal of biomedical nanotechnology, 2017, 13(4): 393-408.

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