mPEG-cRGD, MW 2k

  • Catalog No.
  • BPG-1555
  • Product Name
  • mPEG-cRGD, MW 2k
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • Arg-Gly-Asp (RGD) polypeptide is a common tumor active targeting polypeptide that can directly act on tumor targets to form an active targeting effect. The applications of RGD peptides includes inhibition of apoptosis, angiogenesis and tumor formation. RGD peptides are used as coating surfaces for biomaterials to enhance drug delivery and imaging for disease diagnosis. PEGylated RGD can be cross-linked with other molecules via reactive terminal groups on PEG for use in various biomedical studies.
  • References
  • 1. Wang Y M, Lin J, Kao Y T, et al. Synthesis and characterization cRGD-PEG iron oxide nanoparticles of noninvasive imaging for targeting αvβ3 integrins by MRI.Proc Intl Soc Mag Reson, 2009, 17: 2340.
    2. Xiao Z, Chan L, Zhang D, et al. Precise delivery of a multifunctional nanosystem for MRI-guided cancer therapy and monitoring of tumor response by functional diffusion-weighted MRI.Journal of Materials Chemistry B, 2019, 7(18): 2926-2937.

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