mPEG-AA, MW 20k

  • Catalog No.
  • BPG-0007
  • Product Name
  • mPEG-AA, MW 20k
  • Alias
  • mPEG-Acetic acid; mPEG-CM
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in regular aqueous solution as well as most organic solvents.
  • Description
  • mPEG-AA can be used to modify polypeptides, proteins and other materials with reactive groups. The carboxyl group can easily form a stable amide bond with an amino group, and can also form an ester bond with a hydroxyl group. Polyethylene glycol can increase solubility and stability. It also inhibits the non-specific binding of the charged molecule to the modified surface by reducing the immunogenicity of the polypeptide and protein.
  • References
  • 1. Zalipsky S. Chemistry of polyethylene glycol conjugates with biologically active molecules. Advanced Drug Delivery Reviews, 1995, 16(2-3): 157-182.
    2. Abuchowski, Abraham, et al. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. Journal of Biological Chemistry, 1977, 252(11): 3582-3586.

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