MAL-PEG-PCL, MW 600

  • Catalog No.
  • BPG-1380
  • Product Name
  • MAL-PEG-PCL, MW 600
  • Alias
  • PCL-PEG-MAL
  • Storage
  • -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
  • Solubility
  • Soluble in water, DMSO and DMF. Freshly prepared before use.
  • Description
  • Polyethylene glycol and polycaprolactone coupled compounds are widely used in the field of biomedicine. Drugs modified by the PEG-PCL series of derivatives have better water solubility, encapsulation efficiency and drug loading. PEGylation can improve the stability of the drug. PCL has good biocompatibility, degradability and other properties. It does not cause toxic side effects to the human body and can therefore be used as a carrier material for different types of drugs. In addition, PCL has good flexibility, slow degradation rate and good film formation, so it can be used for postoperative tissue engineering.
  • References
  • 1. Gao H, Qian J, Cao S, et al. Precise glioma targeting of and penetration by aptamer and peptide dual-functioned nanoparticles. Biomaterials, 2012, 33(20): 5115-5123.
    2. Zhang P, Hu L, Yin Q, et al. Transferrin-conjugated polyphosphoester hybrid micelle loading paclitaxel for brain-targeting delivery: synthesis, preparation and in vivo evaluation. Journal of Controlled Release, 2012, 159(3): 429-434.

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