-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
Soluble in water, DMSO and DMF. Freshly prepared before use.
GAA-PEG-GAA has two identical activated terminal groups. This Homobifunctionalized PEG derivatives have wide applications in peptides, proteins, lipids, other small molecules and surface modifications. Drug PEGylation can alter its dispersity and solubility in aqueous solutions. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system.
1. Singh, Anirudha, et al. Enhanced lubrication on tissue and biomaterial surfaces through peptide-mediated binding of hyaluronic acid. Nature materials, 2014, 13(10): 988. 2. Chen, Tao, et al. Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging. ACS nano, 2011, 5(10): 7866-7873.