Synonyms: Four-Arm PEG-Glutaric Acid; Four-Arm polyethylene glycol-GA; Four-Arm PEG-GA
Four-Arm PEG-Glutaric Acid (4-Arm PEG-GA) is a multiarm PEG derivative with carboxylic acid groups at each terminal of the four arms connected to one pentaerythritol core. It is usually a solid powder or particle, which needs to be protected by inert gas, frozen and dissolved in some organic reagents such as dimethyl sulfoxide and dimethylformamide. There is a C4 ester linkage between PEG and the glutaric acid COOH group. PEG acid can be used to react with amine groups with peptide coupling reagents such as NHS and DCC, EDC. Four arm polyethylene glycol derivatives have a variety of active groups that can be used to modify proteins, peptides and other materials through their functional groups.
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