Azido-PEG4-propionic acid
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1898 |
| Product Name | Azido-PEG4-propionic acid |
| CAS | 1257063-35-6 |
| Molecular Formula | C11H21N3O6 |
| Molecular Weight | 291.30 |
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| Description | Azido-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | Azido-PEG4-acid;N3-PEG4-COOH; Azido-PEG4-C2-acid; Azido-PEG4-Acid; N3-PEG4-CH2CH2COOH; 1-Azido-3,6,9,12-tetraoxapentadecan-15-oic acid; 15-Azido-4,7,10,13-tetraoxapentadecanoic acid |
| IUPAC Name | 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)O |
| InChI | InChI=1S/C11H21N3O6/c12-14-13-2-4-18-6-8-20-10-9-19-7-5-17-3-1-11(15)16/h1-10H2,(H,15,16) |
| InChIKey | BODPHGOBXPGJKO-UHFFFAOYSA-N |
| Purity | ≥95% |
| Solubility | Soluble in DMSO (10 mm) |
| Appearance | Colorless to light orange to yellow clear liquid |
| Storage | Store at 2-8°C |
| Exact Mass | 291.14303540 |
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Technical Information
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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