-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.
Soluble in water, DMSO and DMF. Freshly prepared before use.
The 8-arm PEG derivative has a larger molecular weight and can carry more drug molecules. The 8-arm PEG derivative has a branched or comb-like structure. Multi-arm PEG derivatives are commonly used in drug delivery systems. The molecular weight of the modified drug is increased and is not easily eliminated by metabolism in the body. In addition, the dispersibility and solubility of the modified drug in the body are improved. Multi-arm PEG derivatives can also modify the surface of biological materials or form new biomedical materials.
1. Zhao X, Milton Harris J. Novel degradable poly (ethylene glycol) hydrogels for controlled release of protein. Journal of pharmaceutical sciences, 1998, 87(11): 1450-1458. 2. Harris J M. Delivery of poly (ethylene glycol)-modified molecules from degradable hydrogels: U. S. Patent 6,258,351. 2001-7-10.