SPDP-Val-Cit-PAB-OH

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Category	SPDP Peptide
Catalog NO.	BPG-4434
Product Name	SPDP-Val-Cit-PAB-OH
Molecular Formula	C26H36N6O5S2
Molecular Weight	576.7

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Product Information

Description	SPDP-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit was designed specifically be cleaved by Cathepsin B. Pyridyldithiol reactive group enables disulfide linkage with reduced cysteines and other sulfhydryl molecule, providing a stable but cleavable bond. Please contact us for GMP-grade inquiries.
Synonyms	OPSS-Val-Cit-PAB-OH; SPDP-Val-Cit-PAB-OH; AKOS040743746; BP-24350; HY-141144; CS-0115580; (2S)-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]-2-[[(2S)-3-methyl-2-[3-(pyridin-2-yldisulfanyl)propanoylamino]butanoyl]amino]pentanamide
IUPAC Name	(2S)-5-(carbamoylamino)-N-[4-(hydroxymethyl)phenyl]-2-[[(2S)-3-methyl-2-[3-(pyridin-2-yldisulfanyl)propanoylamino]butanoyl]amino]pentanamide
Canonical SMILES	CC(C)C(C(=O)NC(CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)CO)NC(=O)CCSSC2=CC=CC=N2
InChI	InChI=1S/C26H36N6O5S2/c1-17(2)23(32-21(34)12-15-38-39-22-7-3-4-13-28-22)25(36)31-20(6-5-14-29-26(27)37)24(35)30-19-10-8-18(16-33)9-11-19/h3-4,7-11,13,17,20,23,33H,5-6,12,14-16H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H3,27,29,37)/t20-,23-/m0/s1
InChIKey	JBNULYGGLPZGSV-REWPJTCUSA-N
Purity	0.98
Storage	-20°C

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